LPAR4 Schematic (IMAGE)

University of California - San Diego

LPAR4 Schematic

Caption

Schematic: When a tumor-initiating cell experiences isolation stress, it begins expressing LPAR4. This leads to the production of a new extracellular matrix full of fibronectin (FN1), which keeps the cell safe and recruits other cells into the niche to begin tumor formation.

Credit

UC San Diego Health Sciences

Usage Restrictions

Use photo credit

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.