Heart tissue (IMAGE) University of North Carolina Health Care Caption Heart tissue from untreated mice (left) and heart tissue from mice exposed to a kinase inhibitor called trametinib (right) demonstrates that trametinib causes atrophy of heart muscle cells. Credit Jensen Lab Usage Restrictions N/A License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.