Duplicated Enh14 regions act in concert to upregulate Sox9 (IMAGE)

Hokkaido University

Duplicated Enh14 regions act in concert to upregulate Sox9

Caption

In the Amami spiny rat, the Enh14 region is duplicated. The two copies of Enh14 act in concert to upregulate Sox9, which causes the differentiation of the testes. TES, Enh13 and Enh8 are other regulators of Sox9 (Miho Terao, Yuya Ogawa, et al. Proceedings of the National Academy of Sciences. November 28, 2022).

Credit

Miho Terao, Yuya Ogawa, et al. Proceedings of the National Academy of Sciences. November 28, 2022

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