Figure 1. Schematic illustration of UCNPs for the super-resolution quantification of surface biomarkers on single tumour cell-derived sEVs. (IMAGE)

Light Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CAS

Figure 1. Schematic illustration of UCNPs for the super-resolution quantification of surface biomarkers on single tumour cell-derived sEVs.

Caption

(a) sEVs carrying heterogeneous distribution of biomarkers are released from the tumour cell. (b) sEVs can be captured on an antibody-coated plate and labelled by UCNPs. (c) UCNPs -EV conjugates detected as single bright spots with different intensities can be super-resolved in super-resolution nanoscopy.

Credit

by Guan Huang, Yongtao Liu, Dejiang Wang, Ying Zhu, Shihui Wen, Juanfang Ruan, Dayong Jin

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Credit must be given to the creator.

License

CC BY

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