Single cell sequencing (IMAGE)
Caption
For single cell sequencing, scientists first have to isolate the cell nuclei. When these nuclei pass over a microfluidic chip, they are packed into small aqueous droplets along with a barcode. In the droplets, the barcode is then coupled with the RNA from the nucleus - the transcripts that are generated when the genes are read from the DNA. This way, the RNA can be assigned to the individual cell nuclei after sequencing.
Credit
Eric Lindberg, MDC
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