Single-cell transcriptome profiles of mouse ILNs during the early stage of bubonic plague (IMAGE)

Science China Press

Single-cell transcriptome profiles of mouse ILNs during the early stage of bubonic plague

Caption

Single-cell RNA sequencing was performed in the lymph nodes of mice at 2h and 24h post infection with Y. pestis, which showed that inflammation related pathway genes were significantly up-regulated in the early stage of infection. Compared with T cells and B cells, innate immune cells tended to interact with Y. pestis during the early stage of infection.

Credit

©Science China Press

Usage Restrictions

Use with credit.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.