modified-RNA CRISPR method (IMAGE) Penn State Caption The modified-RNA CRISPR method developed by Penn State researchers provides higher gene editing efficiency and no risk of vector insertion into the human cell genome. Credit Penn State Usage Restrictions No restrictions. License Public Domain Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.