TIS window for bilateral cortical observation post-TBI. (IMAGE)

Light Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CAS

TIS window for bilateral cortical observation post-TBI.

Caption

a Fluorescence imaging of a TBI mouse on a centimeter scale. b-d Larger views of the three areas in (a). e-g The results of neutrophil and vessel segmentations in (b)-(d), respectively. h-j Tracked neutrophils in each ROI. k-l The relationship between the travel distance and the distance to (k) the injury center or (l) the midline. m-n The relationship between the travel velocity and the distance to (m) the injury center or (n) the midline. o-r Quantitative analyses of neutrophil cytodynamics in three ROIs. s Fluorescence imaging of another TBI mouse showing bleeding across several hours of observation. t Enlarged view of the area in the solid blue line box in (s). u Changes in the average velocity of neutrophils in the area during observation. t1 denotes when the bleeding started. t2 indicates when the bleeding spread to the area.

Credit

by Dongyu Li, Zhengwu Hu, Hequn Zhang, Qihang Yang, Liang Zhu, Yin Liu, Tingting Yu, Jingtan Zhu, Jiamin Wu, Jing He, Peng Fei, Wang Xi, Jun Qian and Dan Zhu

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License

CC BY

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