Fig2. (IMAGE) Osaka University Caption Mice lacking Runx1/2 in CAR cells display severe defects of hematopoiesis (A) and massive fibrosis (B) in the bone marrow. Credit 2022 Yoshiki Omatsu et al. Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells. Nature Communications. Used under CC BY (https://creativecommons.org/licenses/by/4.0/). Only text in the figure was changed from original. Usage Restrictions Credit must be given to the creator. License CC BY Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.