Figure 2 (IMAGE) The Protein Society Caption Figure 2 Mechanism of Z-PYP, a chimera in which photoactive yellow protein (PYP) is inserted into a loop of the Z-domain (blue and purple). In the dark, PYP is folded (yellow) and prevents folding of the Z-domain. Exposure to blue light results in the destabilization of PYP (gray), enabling folding of the Z-domain, which can then bind to the Fc portion of an IgG molecule (green). Adapted from Figure 1C of Woloschuk, Reed, et al. (Protein Sci 2021 doi: 10.1002/ pro.4196). Credit Adapted from Figure 1C of Woloschuk, Reed, et al. (Protein Sci 2021 doi: 10.1002/ pro.4196). Usage Restrictions None License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.