Fig. 1 Single-cell RNA-seq analysis of AGM. (IMAGE)

Kobe University

Fig. 1 Single-cell RNA-seq analysis of AGM.

Caption

a: Experimental schematic. Cells are isolated from the fetal yolk sac and AGM and their transcripts are sequenced by next-generation sequencing. b: Cell groups from single-cell analysis of AGM progenitor cells are shown. c: Heatmap of top 10 enriched genes in the three cell groups (6, 12, 17) in b. d: Gene enrichment analysis based on protein-protein inter-network of RUNX1, a transcription factor essential for the endothelial-to-hematopoietic transition (EHT), in which vascular endothelial cells give rise to hematopoietic stem cells.

Credit

Figure derived from the paper published in Molecular Psychiatry (2022) (DOI：10.1038/s41380-022-01566-y)

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