Figure 4 (IMAGE)
Caption
Transcriptional repression by promoting histone deacetylase 1 (HDAC1) affects the process from vascular endothelial cells to the production of hematopoietic stem cells (EHT). Erythroid/myeloid progenitor cells (EMP) in the yolk sac (Yolk sac) activate microglia and affect inflammation in the brain; pre-HSC in AGM differentiate in the bone marrow (BM); and the altered immune system affects the gut microbiota.
Credit
Figure derived from the paper published in Molecular Psychiatry (2022) (DOI:10.1038/s41380-022-01566-y)
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License
CC BY