Screening Method for Cyclic Peptides that Help Nanoparticles Penetrate the Blood-Brain Barrier (IMAGE)

Kumamoto University

Screening Method for Cyclic Peptides that Help Nanoparticles Penetrate the Blood-Brain Barrier

Caption

A Kumamoto University research group collected phages that penetrate human blood-brain barrier model cells and analyzed the amino acid sequence of the peptides on the permeating phages.

Credit

Professor Sumio Ohtsuki

Usage Restrictions

<p>Reprinted from Fig. 1A of the <a href="https://www.sciencedirect.com/journal/journal-of-controlled-release">Journal of Controlled Release</a>, 321, Yamaguchi, S., Ito, S., Masuda, T., Couraud, P.-O., & Ohtsuki, S, "Novel cyclic peptides facilitating transcellular blood-brain barrier transport of macromolecules in vitro and in vivo," 744-755, Copyright 2020, doi:10.1016/j.jconrel.2020.03.001 with permission from Elsevier. It has been modified in the following manner: The text has been reduced & simplified for use as a press release.</p> <p>This image may not be reproduced without permission from Elsevier.</p>

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.