Blood Vessel around Tumors before and after Treatment with ABTAA (IMAGE)

Institute for Basic Science

Blood Vessel around Tumors before and after Treatment with ABTAA

Caption

Schematic drawing of a blood vessel around tumors before and after treatment with ABTAA. The picture above shows a typical tumor vasculature characterized by damaged walls, red blood cells leakage and detached pericytes. Activating Tie2 on endothelial cells with the antibody ABTAA restores the normal vessel architecture: endothelial and pericytes on the vessel walls are stabilized, the delivery of blood is improved, and the anticancer drugs are more likely to reach the tumor core.

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Institute for Basic Science (IBS)

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