CETP Moving Cholesterol from HDL to LDL (IMAGE)

DOE/Lawrence Berkeley National Laboratory

CETP Moving Cholesterol from HDL to LDL

Caption

(1) CETP penetrates HDL to its cholesterol core. (2) Upon interaction with LDL/VLDL, molecular forces cause the formation of pores at either end of CETP. (3) These pores connect with CETP’s central cavities to form a tunnel for the transfer of cholesterol to LDL/VLDL, which (4) reduces HDL in size.

Credit

Image by Gang Ren, Lawrence Berkeley National Laboratory

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