A New Way of Mapping the Brain (IMAGE)

Cold Spring Harbor Laboratory

A New Way of Mapping the Brain

Caption

Left: Single-neuron tracing reveals the projections of a single neuron in the mouse brain. It took the team 3 years to map 31 such neurons. In 3 weeks and at a fraction of the cost, MAPseq discovered the destinations of 591 neurons in the mouse primary visual cortex, reaching similar conclusions about projection patterns. The 'readout' is dramatically different (right), showing 8 projection 'motifs' (8 clusters, read horizontally), with strength of connections in parts of the higher visual cortex displayed in color intensities.

Credit

Zador Lab, CSHL

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