HE-OX40 Treatment Can not Induces Hepatitis in Casp KO Mice (IMAGE)

Houston Methodist

HE-OX40 Treatment Can not Induces Hepatitis in Casp KO Mice

Caption

Without the signaling molecule caspase-1, OX40 proteins do not induce inflammatory cell death in the liver, showing normal blood vessels (white section in the middle) of a genetically-modified mouse. Liver cells (hepatocytes) are arranged in structures (purple circles) that radiate away from the blood vessel.

Credit

Houston Methodist

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.