(IMAGE)

Kumamoto University

Caption

Extracellular vesicles released from radiation-resistant oral cancer cells are taken up by radiation-sensitive cells, which release miR-503-3p. The released miR-503-3p suppresses BAK, a protein that promotes apoptosis, thereby preventing radiation-induced cell death (apoptosis). As a result, radiation-sensitive cells acquire radioresistant.

Credit

From Fig. 6E of Yamana K., et.al., Journal of Extracellular Vesicles, 2021. The image has been modified for use and clarity within this release.

Usage Restrictions

Credit must be given to the creator. Only noncommercial uses of the work are permitted.

License

CC BY-NC

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.