(IMAGE)
Caption
(Left) The expression levels of microRNAs in extracellular vesicles extracted from chemoradiation-responder and chemoradiation-non responder patients were compared, and 42 microRNAs were picked up that were elevated in the inactive patients. (Right) The expression levels of microRNAs in extracellular vesicles extracted from radiation-sensitive and radiation-resistant cells were compared, and 142 microRNAs were picked up. (Mid-bottom) Preliminary experiments were conducted using three macroRNAs whose expression was up-regulated in both, and finally miR-503-3p was identified as a microRNA involved in radioresistance.
Credit
Dr. Ryoji Yoshida
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