Lgr5 (in Green) Marks Adult Intestinal Stem Cells (2 of 2) (IMAGE)

University of California - San Francisco

Lgr5 (in Green) Marks Adult Intestinal Stem Cells (2 of 2)

Caption

Lgr5 (in green) marks adult intestinal stem cells, and is lost in crypts near granulomas. EdU (in red) marks proliferative cells. Granuloma-associated crypts lacking Lgr5+ ISCs are hyper-proliferative relative to normal crypts. Cell nuclei are visible in blue.

Credit

Image by Ysbrand Nusse.

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