Figure 2: Psychomotor Vigilance (IMAGE) Radiological Society of North America Caption Psychomotor vigilance Task. A, Repeated-measures analysis of variance (ANOVA) results of the attention phase of the psychomotor vigilance task superim¬posed to a standard brain template (colors indicate P values of significant voxels, cluster-based P ? .05; cluster size, K ? 10) shows positive drug X time interactions in favor of a methylene blue effect in the bilateral anterior and posterior insular cortices (n = 26, with 24 degrees of freedom). B, Representative block from the psychomotor vigilance task shows the stimulus, attention, reaction, feedback, and rest phases as demarcated by set times. Credit Radiological Society of North America Usage Restrictions May use with credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.