DNAJC13 (IMAGE)

Osaka University

DNAJC13

Caption

Mutant DNAJC13 impairs cargo transport from early to recycling endosomes. A: Mutant DNAJC13 exhibited less colocalization with F-actin compared with wt DNAJC13, indicating Mutant DNAJC13 disrupts actin cytoskeletal organization on endosomal surface. B: Aberrant retention of αSYN in the endosomal compartment was observed in cells expressing mutant DNAJC13 compared with mock or wt DNAJC13 transformants.

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Tohoku University

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