Figure 1 (IMAGE) Osaka University Caption Model for the gene regulatory pathway by RamR. RamR represses the ramA gene, which encodes a protein that activates acrAB drug efflux pump genes. RamR binds to the region between the ramR and ramA genes, while RamA binds to the upstream region of acrAB. Credit Osaka University Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.