Isolation membrane expansion (IMAGE) Japan Science and Technology Agency Caption Figure 2: Lipid scrambling by Atg9 enables isolation membrane expansion Atg2 transfers lipids from the endoplasmic reticulum to the cytoplasmic leaflet of the isolation membrane, which are then distributed to both leaflets by the scramblase activity of Atg9, enabling isolation membrane expansion. Credit Nobuo N. Noda & Kazuaki Matoba Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.