Figure 1 (IMAGE)

Institute for Basic Science

Figure 1

Caption

Cancer cells tend to accumulate many mutations during their growth. These include single base substitutions, small insertion/deletions (InDel), and large chromosomal changes. Researchers made CRISPR-Cas9 reagents targeting tumor-specific InDel mutations that can induce numerous double-strand breaks in the DNA of cancer cells, effectively killing them. Because normal cells do not have these cancer-specific mutations, only tumor cells will be destroyed.

Credit

Institute for Basic Science

Usage Restrictions

Attribution Required

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.