Figure 2: Mechanism of the Two Modes of Programmed Cell Death Induced by Caspase-1 (IMAGE)
Caption
Caspase-1 induces pyroptosis in those cells that express gasdermin D such as macrophages. On the other hand, in the case of those cells like neurons that do not express gasdermin D, it induces apoptosis though Bid activation.
Credit
Kanazawa University
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