Restoring Enzyme Function with a 'Shim' (VIDEO) Indiana University School of Medicine This video is under embargo. Please login to access this video. Caption Thomas Hurley of the Indiana University School of Medicine demonstrates how a the compound Alda-1 works to restore functionality to a mutated form of the enzyme ALDH2, which plays an important role in metabolizing alcohol and other toxins in the body. Credit Eric Schoch / Office of Public and Media Relations, Indiana University School of Medicine Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.