Fig. 1 MondoA depletion promotes senescence (IMAGE) Osaka University Caption Staining images of SA-b-gal-positive senescent cells (blue). In siMondoA-treated cells, SA-b-gal positivity was increased, even in a doxorubicin-induced senescence model. Credit 2022 Yamamoto-Imoto et al. Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis. Cell Reports Usage Restrictions Credit must be given to the creator. License CC BY Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.