Figure 2 (IMAGE) Institute for Basic Science Caption Induction of heterosynaptic LTD with homosynaptic LTP at the time of initial learning enables flexible memory formation and allows for cognitive flexibility. Lack of heterosynaptic LTD causes inflexible memory to be formed, which makes it difficult to learn new information because the memory cannot be modified properly. Credit Institute for Basic Science Usage Restrictions Attribution Required License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.