Low dose metformin improved renal function, inflammation, and fibrosis in a ND-CKD (Alport syndrome) mouse model (IMAGE)

Kumamoto University

Low dose metformin improved renal function, inflammation, and fibrosis in a ND-CKD (Alport syndrome) mouse model

Caption

Low dose metformin was found to have a nephroprotective effect similar to losartan.

Credit

Professor Hirofumi Kai

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<p>Adapted from Figs. 1b & 1d (top) and Figs. 2d & 2c (bottom) of <a href="https://www.nature.com/articles/s41598-021-86109-1" target="_blank">Omachi, K. et.al., Scientific Reports, 2021</a>. </p> <p>This image is made available under the terms of <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">CC by 4.0</a>. Any further distribution of this work must follow the terms of this license. </p>

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