mTOR Inhibition Suppresses Kidney Crystal Formation (IMAGE)

Nagoya City University

mTOR Inhibition Suppresses Kidney Crystal Formation

Caption

Numbers of GFP-MAP1LC3 puncta (white arrows) and autophagosomes (black arrows) in renal tubular cells were increased with mTOR inhibitor of GFP-MAP1LC3-mice treated with GOX. This means the activation of autophagy. Amount of crystals formed in kidneys extracted from mice after GOX and mTOR inhibitor injection was suppressed.

Credit

Takahito Yasui, M.D., Ph.D.

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.