Functions of Normal and Oncogenic RNF43 (IMAGE)

Hokkaido University

Functions of Normal and Oncogenic RNF43

Caption

Normal RNF43 acts as a tumor suppressor when activated by the addition of phosphate groups (phosphorylation), whereas mutant RNF43 cannot be phosphorylated due to the oncogenic mutations. (Tadasuke Tsukiyama, et al., Nature Communications, September 15, 2020)

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Tadasuke Tsukiyama, et al., Nature Communications, September 15, 2020

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