Oncogenic RNF43 and Cancer (IMAGE)

Hokkaido University

Oncogenic RNF43 and Cancer

Caption

Oncogenic RNF43 which induces aberrant activation of Wnt signaling and suppression of an important tumor suppressor gene p53 at the same time, interacts with active Ras in a multi-step carcinogenesis process (Tadasuke Tsukiyama, et al., Nature Communications, September 15, 2020).

Credit

Tadasuke Tsukiyama, et al., Nature Communications, September 15, 2020

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