Visualizing CRISPR in Action (IMAGE) Harvard Medical School Caption This is an cryo-electron microscope image of CRISPR in a full 'R-loop' conformation. DNA (orange and red) is unwound and compared to CRISPR RNA (blue), to determine if the target DNA should be cut by the Cas3 enzyme. Credit Liao lab/Harvard Medical School Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.