Fig.3 The mechanism of the fasting response in adipocytes (IMAGE)

Osaka University

Fig.3 The mechanism of the fasting response in adipocytes — Caption

Adipose autophagy is induced with fasting, thereby degrading Rubicon to further promote autophagy. Autophagy in adipocytes degrades SRC-1 and TIF2, and their reduction leads to a decrease in adipogenic gene expression and fat mass. Fat is transferred from adipose tissue to the liver and used for ketone body production.

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Tadashi Yamamuro et al.

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