AND Gate (IMAGE)

University of Washington

AND Gate

Caption

Representation of an "AND" gate, which is only open when separate triggers (A and B) cleave both the green and purple regions of the gate, respectively. At right is the chemical structure of a specific "AND" gate. The region shown in green is a short peptide that can be cleaved by tumor-associated enzyme MMP. The purple region is a synthetic chemical group called an ortho-nitrobenzyl ester (oNB), which can be cleaved by focused light.

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University of Washington

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