Setd1a Deficiency Disrupts Axonal Growth (IMAGE)

The Zuckerman Institute at Columbia University

Setd1a Deficiency Disrupts Axonal Growth

Caption

Representative image showing differences in axon terminal branching from the brains of normal mice (left) compared to mice with lower levels of SETD1A.

By administering an LSD1 inhibitor in adult SETD1A-deficient mice, the researchers rescued this stunted growth to near-normal levels.

Credit

Jun Mukai/Gogos lab/Columbia's Zuckerman Institute

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