Figure 2. (IMAGE) Osaka University Caption The role of the PI3K/Hippo pathway in chronic pancreatitis. Mice lacking PTEN/SAV1 spontaneously develop chronic pancreatitis with inflammation, fibrosis and atrophy of the pancreas. Credit Osaka University Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.