CRISPR-Gold Nanoparticles (IMAGE)

University of California - Berkeley

CRISPR-Gold Nanoparticles

Caption

To make CRISPR-Gold, a CRISPR delivery system, a gold nanoparticle is covered with a forest of DNA oligonucleotides and decorated with Cas9 ribonucleoproteins, complexes of protein and guide RNA. It is then covered with a polymer that helps the particle get taken up by cells, in this case, neurons, astrocytes and microglia in the brain.

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UC Berkeley

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