CRISPR-Gold Nanoparticles (IMAGE) University of California - Berkeley Caption To make CRISPR-Gold, a CRISPR delivery system, a gold nanoparticle is covered with a forest of DNA oligonucleotides and decorated with Cas9 ribonucleoproteins, complexes of protein and guide RNA. It is then covered with a polymer that helps the particle get taken up by cells, in this case, neurons, astrocytes and microglia in the brain. Credit UC Berkeley Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.