Neurons Are Defined by the Machinery that Enables Them to Communicate (IMAGE)
Caption
Patterns of cell-to-cell communication are the core feature making possible rigorous distinctions among neuron types across the mouse brain. Cell-defining features fell into just six functional categories of gene families, all vital for cell-to-cell communications. They include proteins that are expressed on either side of the communications interface in neurons (all the elements tinted red): along or near membranes that face one another across the synaptic gap - the narrow space separating a (pre-synaptic) neuron sending a signal and a (post-synaptic) neuron facing it which receives the signal.
Credit
Huang Lab, CSHL
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