illustration (IMAGE) UT Southwestern Medical Center Caption The binding of CTLA-4 antibodies throughout the body limits their anti-tumor effect. In contrast, a newly developed two-armed molecule that targets both CLTA-4 and CD47 on regulatory T cells efficiently hones in on tumors and enhances antitumor immunity. Credit UT Southwestern Medical Center Usage Restrictions None License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.