Doudna, Nogales, et al (IMAGE) DOE/Lawrence Berkeley National Laboratory Caption From left, Blake Wiedenheft, Eva Nogales, Gabriel Lander and Jennifer Doudna, used a combination of cryo-electron microscopy and 3-D image reconstruction to determine the structure of Cascade, a protein complex that detects and inactivates invading pathogens. Credit Photo by Roy Kaltschmidt, Berkeley Lab Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.