Potential New Cancer Treatment Activates Cancer-Engulfing Cells: Figure 3 (IMAGE)

Kobe University

Potential New Cancer Treatment Activates Cancer-Engulfing Cells: Figure 3

Caption

Figure 3: Anti-tumor effects of anti-SIRPα antibodies applied independently (A) High expression of SIRPα in human renal cell carcinoma and melanoma (B) Tumor-killing effects of anti-SIRPα antibodies in mice with subcutaneous mouse renal cell carcinoma (RENCA). The anti-SIRPα antibodies inhibit the CD47-SIRPα binding, demonstrating a stronger anti-tumor effect compared to those without the binding inhibition (C) A model of the dual-action anti-tumor effect of anti-SIRPα antibodies on renal cell carcinoma and melanoma, both of which show a high expression of SIRPα

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Kobe University

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