Circuits Encoding Positive and Negative Learned Associations (IMAGE)

NIH/National Institute of Mental Health

Circuits Encoding Positive and Negative Learned Associations

Caption

The researchers pinpointed separate brain circuits for positive and negative associations in mouse brain by injecting retrograde fluorescent bead tracers (green, red) that migrated upstream through neuronal projections linking a reward center (NAc, nucleus accumbens) and a fear center (CeM, centromedial amygdala) to an emotional memory crossroads (BLA, basolateral amygdala).

Credit

Praneeth Namburi, Anna Beyeler, Ph.D., Kay M. Tye, Ph.D., Massachusetts Institute of Technology

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