Changes in the Dentate Gyrus are Associated with Normal Age-Related Memory Decline (IMAGE)

Columbia University Irving Medical Center

Changes in the Dentate Gyrus are Associated with Normal Age-Related Memory Decline

Caption

The dentate gyrus is distinct from the entorhinal cortex, the hippocampal region affected in early-stage Alzheimer's disease. Previous work, including by the laboratory of senior author Scott A. Small, M.D., had shown that changes in a specific part of the brain's hippocampus -- the dentate gyrus -- are associated with normal age-related memory decline in humans and other mammals.

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Lab of Scott A. Small

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