Molecular Models (IMAGE)

University of Texas at Austin, Texas Advanced Computing Center

Molecular Models

Caption

Because of the complexity of the human dopamine transporter structure, the models used to investigate the effects of drugs of abuse and neurological disorders are based on similar crystal structures from the bacterial transporter, LeuT (grey) and the Drosophila melanogaster fly (red). This image shows the superimposition of those molecular models and their binding sites and the location of two of the mutations in the dopamine transporter identified in the published work.

Credit

Dr. Michelle Sahai

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