ATRX and Chromosome Stability (IMAGE)

University of Georgia

ATRX and Chromosome Stability

Caption

ATRX is required to maintain chromosome stability. Genome-wide analysis by spectral karyotyping reveals that loss of ATRX function in mouse cells results in centromeric breaks and chromosome translocations. Insets illustrate the translocation of a fragment of chromosome 16 into the centromeric region of chromosome 17.

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University of Georgia

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