Chaperone-mediated Autophagy (IMAGE)
Caption
Chaperone-mediated autophagy in a neuron: A protein chaperone (red circle) escorting a molecule of damaged tau protein (green) docks with a LAMP2 receptor (blue) on the cell's lysosome (orange) and pushes the tau protein inside the lysosome, where it is digested.
Credit
Courtesy of Albert Einstein College of Medicine
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