Pheromones ration body fat and facilitates longevity in dauer larvae (IMAGE)
Caption
On the left, the expression of fat burning enzymes (green) is the lowest in normal larvae (WT), but higher in gene deletion mutant larvae (acox-3) that synthesize less pheromones, and the highest in mutant larvae (acox-Δ7 & daf-22) that synthesize no pheromones. In the center, the pheromone-less acox mutant dauer larvae store less fat than WT (fat storing lipid droplets stained red). On the right, during hunger, the pheromone-less acox mutant dauer larvae live shorter than WT. Photo credit: Cheng Gao and Shaobing O. Zhang.
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