2 States of TFIID (IMAGE)

DOE/Lawrence Berkeley National Laboratory

2 States of TFIID

Caption

The TFIID transcription factor protein co-exists in two states: Canonical, in which the lobe A is connected to the lobe C; and rearranged, in which the lobe A is connected to the lobe B. Only in the rearranged state does TFIID bind to DNA.

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(Image courtesy of Nogales Lab)

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